Archive for January 2013
Myocutaneous Island Flap – Upper Lip Reconstruction
Mohs excision of upper lip philtrum squamous cell carcinoma left a subtotal lip defect. Bilateral nasolabial fold myocutaneous island advancement flaps were used to successfully rebuild the functional and aesthetic upper lip. The flaps utilized the outer circumference of orbicularis oris to rebuild the muscular continuity of this large defect. Complete oral competence was restored…
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DNA Molecular Testing and Personalized Medicine – Part 2
Another genetic molecular technology that has evolved tremendously is real time polymerase chain reaction (PCR). When accompanied by reverse transcription prior to PCR (RT-PCR), it has also allowed rapid multiple gene analysis useful for cancer staging such as OncotypeDx. This platform analyzes RNA for 21 genes with RT-PCR to stratify breast cancer patients according to…
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