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Posts Tagged ‘hedgehog pathway’


Vismodegib – A Breakthrough in Basal Cell Carcinoma Treatment

Vismodegib, a Hedgehog Pathway Inhibitor, has been recently shown to be highly effective for advanced basal cell carcinoma in Phase II clinical studies. Discovery of the Hedgehog Signaling Pathway is enlightening in how three unrelated basic science research paths can meet at crossroads of cancer treatment breakthrough. First, there were sheep in Idaho in 1957…

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