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Posts Tagged ‘S100’

New Melanoma Staining: SOX10 and MiTF

S-100, tyrosinase, Melan A, and HMB 45 have been the workhorses of melanocyte histopathology. A new immunohistochemical stain, SOX10, has recently been shown to be a useful marker in the diagnosis of melanocytic tumors.  It is strongly expressed by desmoplastic melanoma and is less likely to be expressed by background fibrocytes and histiocytes. Sry-related HMG-BOX…

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