Dermatopathology
Deeply Invasive Squamous Cell Carcinoma of Cheek
HISTORY: 82-year-old man with a 1 year history of squamous cell carcinoma on the right lower cheek biopsied on 4/28/2017. Radical resection of the right cheek carcinoma and deep facial lymph node biopsy was performed. Intraoperative Mohs margin evaluation confirmed clear margins. Final permanent histology margins were close but clear. Evidence of perineural invasion…
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RECURRENT SCALP MELANOMA WITH CALVARIAL METASTASES
HISTORY 85-year-old man presented in 4/2016 with a 4 month history of a nonhealing scalp wound following excision of melanoma done in 2014, then additional excision with skin graft closure followed by radiation completed in June 2015. The wound developed skin breakdown and osteoradionecrosis treated with serial outer table of calvarium debridements. Recent biopsy on…
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Recurrent Extensive Basal Cell Carcinoma of Forehead
HISTORY 68-year-old man presented with a recurrent right forehead basal cell carcinoma. The carcinoma was previously treated with Mohs excision in 2002 and 2009. The recurrence appeared initially as superficial and was treated successfully with topical imiquimod. Deep recurrence became evident many months later. Morphology of the basal cell carcinoma was infiltrative with metatypical features.…
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Lower Leg Radiation Ulcer
HISTORY 85-year-old man presented in March 2015 with a multi-year history of a non-healing right lower leg lesion. Shave biopsy found squamous cell carcinoma in situ with focal areas of early invasion. Superficial radiotherapy was prescribed at 50 kvp 5 days per week for 5 weeks ending in July 2015. Minor skin erosion present 3…
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Sclerosing Adnexal Carcinoma of Nose
HISTORY 74-year-old man presented in June 2017 with 2-month history of scabbing of the left nose. A biopsy performed 5/11/17 revealed sclerosing carcinoma of left nose. The lesion is an 8mm plaque at the base of the left nasal ala. Mohs and reconstruction are being planned. DISCUSSION The histology of the sclerosing carcinoma is presented…
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CONJUCTIVAL SQUAMOUS CELL CARCINOMA
HISTORY 69 year old man presented in August 2016 for a large papillomatous lesion of the left inferior cornea. Patient has a history of left lower eyelid basal cell carcinoma that was treated in 2014. The area of corneal carcinoma was initially thought to be exposure keratitis. DISCUSSION The patient is a 69-year-old organ transplant…
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