Posts Tagged ‘Sentinel Lymph Node Biopsy’
A Modern Test for Melanoma
DecisionDx Melanoma is enhancing medical decision making in invasive melanoma stages I, II, and III.. Management of cutaneous melanoma involves strategic risk assessment and oncologic work-up. This typically includes staging, wide local excision, and possible sentinel lymph node biopsy or biologic therapy. Traditionally, surgeons perform a sentinel lymph node biopsy (SLNB) if the possibility of…
Read MoreMultiple Cutaneous Carcinomas in Organ Transplant Recipients
HISTORY A 73-year-old kidney transplant recipient presented with multiple carcinomas including SCC, SCC in situ, and BCC of the face and scalp. DISCUSSION Organ transplant recipients can suffer from multiple cutaneous carcinomas. Some lesions can have a high risk of metastases, but most occur in multitudes in areas of extensive sun exposure. At SCARS Center,…
Read MoreSentinel Lymph Node Biopsy for Cutaneous SCC
HISTORY A 58-year-old kidney transplant recipient presented with a 6-month history of squamous cell carcinoma of the left scalp. This large lesion was adjacent to the scar of a previous carcinoma excision in 2014. Patient is on sirolimus for his kidney transplant performed in 1984. He has had multiple BCCs and SCCs of scalp, back,…
Read MoreNear-Infrared Laser Lymphangiography Sentinel Lymph Node Biopsy for Melanoma
HISTORY A 61-year-old male presents for 1.5 cm malignant melanoma of left posterior shoulder invading to at least 1.2 mm (Clark’s Level IV) on a shave biopsy. Left shoulder melanoma was excised, and a left axillary sentinel lymph node was biopsied. Small focus of residual melanoma was found in the primary site, but none in…
Read MoreMelanoma within recurrent MIS
HISTORY 73-year-old woman presents with 1-year history of recurrent pigmented lesion of the right nasal ala found to be invasive melanoma with 0.5 mm invasion. Patient’s history began 9 years ago in 2009 with excision of a melanoma in situ and skin graft closure. In 2012, pigmentation adjacent to the graft site was found…
Read MoreScalp SCC Metastasis to Neck
HISTORY 64-year-old man presents in 11/2017 with tender, right postauricular swelling. Fine needle aspiration biopsy showed squamous cell carcinoma. Extensive squamous cell carcinoma of scalp was treated with 4 levels of Mohs earlier that year in 01/2017. Additional smaller squamous cell carcinoma of the same area of the scalp was treated with Mohs in…
Read MoreRECURRENT MELANOMA
HISTORY 70-year-old woman presents with metastatic melanoma in the right parotid gland region of 1 year duration. Diagnosis was made with a core needle biopsy on 09-08-17. Patient also has small palpable right cervical lymph nodes with SUV 1.6 and 2.0. Patient history of melanoma began in 2001 as a pink macule of the…
Read MoreINVASIVE BOWEN’S CARCINOMA OF CHEEK
HISTORY 79 year old woman presented with a 3 month history of right angle of jaw mass hardening over time. A biopsy of a separate lesion of the right central cheek on 2/21/17 showed papillated Bowen’s Disease. The jaw mass was biopsied on 2/24/17 and revealed invasive Bowen’s carcinoma – squamous cell carcinoma. DISCUSSION This…
Read MoreIs there a Role for Sentinel Lymph Node Biopsy in Cutaneous Squamous Cell Carcinoma?
Sentinel lymph nodes are defined as the first lymph nodes that receive metastases from a primary tumor. The concept of a first echelon node was first described by Seaman and Powers and later given the name “sentinel node” by Gould in 1960. Cabanas established the basis of modern sentinel lymph node theory by advocating that…
Read MoreSTUMP and MelTUMP
Ambiguous melanocytic lesions – those with histopathologic findings without a diagnostic consensus – are divided into thin and thick tumors. Thin lesions appear as dysplastic nevi and have a potential of being part of melanoma in situ or superficial spreading melanoma. We have explored diagnostic and therapeutic considerations of the thin lesions in a previous…
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